This movie contains the quote, "Houston, we have a problem."

The answer is Apollo 13 because the quote "Houston, we have a problem" is famously associated with this movie. In the film, astronauts Jim Lovell, Fred Haise, and Jack Swigert encounter a critical situation aboard their spacecraft during the Apollo 13 mission. James Lovell, played by Tom Hanks, says these iconic words to communicate the distressing situation to the mission control center in Houston. This quote has since become widely recognized in popular culture and is often referenced to symbolize unexpected challenges and the need for quick problem-solving.