What genetic disease is caused by having an extra Y chromosome (XYY)?

Jacob's syndrome, also known as XYY syndrome, is a genetic condition caused by having an extra Y chromosome in males. Individuals with this syndrome have a karyotype of 47, XYY, in which they possess two X chromosomes and two Y chromosomes instead of the typical XY configuration. This extra Y chromosome occurs during sperm production and is generally not inherited from either parent. Jacob's syndrome is associated with specific physical and behavioral characteristics, including tall stature, learning disabilities, delayed language development, and potentially increased aggression or impulsivity.